Professor
Daniel Bulte
BSc PhD PGDipLaTHE SFHEA
Associate Professor
Tutorial Fellow at St Hilda's College
Honorary Senior Research Fellow Wellcome Centre For Integrative Neuroimaging
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Research
Impact
All publications by Professor Bulte
Ramp protocol for non-linear cerebrovascular reactivity with transcranial doppler ultrasound
Hayes G,  Sparks S,  Pinto J,  Bulte DP,  et al. (2025)
Standardized pancreatic MRI-T1 measurement methods: comparison between manual measurement and a semi-automated pipeline with automatic quality control.
Triay Bagur A,  Arya Z,  Waddell T,  Pansini M,  Fernandes C,  Counter D,  Jackson E,  Thomaides-Brears HB,  Robson MD,  Bulte DP,  Banerjee R,  Aljabar P,  Brady M,  et al. (2025)
Models of Cerebrovascular Reactivity in BOLD-fMRI and Transcranial Doppler Ultrasound.
Hayes G,  Sparks S,  Bulte DP,  Pinto J,  et al. (2025)
A simplified method to estimate blood flow velocity and inversion efficiency in the major cerebral arteries using multi-PLD pCASL
Allery F,  Bulte D,  Hocking E,  Blockley N,  Harkin J,  Pinto J,  et al. (2024)
Comparison of 15oxygen positron emission tomography and near-infrared spectroscopy for measurement of cerebral physiology
Simpson J,  Sudhan N,  Hare H,  Donnelly J,  Liu X,  Aigbirhio F,  Fryer T,  Stocks-Gee G,  Smielewski P,  Bulte D,  Coles J,  et al. (2024)
Biomarkers.
Wang C,  Patel R,  Jobbins L,  Reid G,  Hobden G,  Mackay CE,  Ebmeier KP,  Kivimäki M,  Singh-Manoux A,  Bulte D,  Suri S,  et al. (2024)
Estimation of field inhomogeneity map following magnitude-based ambiguity-resolved water-fat separation.
Triay Bagur A,  McClymont D,  Hutton C,  Borghetto A,  Gyngell ML,  Aljabar P,  Robson MD,  Brady M,  Bulte DP,  et al. (2023)
A systematic review of the association between dementia risk factors and cerebrovascular reactivity
Wang C,  Reid G,  Mackay CE,  Hayes G,  Bulte DP,  Suri S,  et al. (2023)
Supplementary Data from Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham JL,  Chu K-Y,  Teoh E,  Chauhan J,  O’Reilly D,  Harris BHL,  Macklin PS,  Bull JA,  Green M,  Rodriguez-Berriguete G,  Prevo R,  Folkes LK,  Campo L,  Ferencz P,  Croal PL,  Flight H,  Qi C,  Holmes J,  O’Connor JPB,  Gleeson FV,  McKenna WG,  Harris AL,  Bulte D,  Buffa FM,  Macpherson RE,  Higgins GS,  et al. (2023)
Data from Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham JL,  Chu K-Y,  Teoh E,  Chauhan J,  O’Reilly D,  Harris BHL,  Macklin PS,  Bull JA,  Green M,  Rodriguez-Berriguete G,  Prevo R,  Folkes LK,  Campo L,  Ferencz P,  Croal PL,  Flight H,  Qi C,  Holmes J,  O’Connor JPB,  Gleeson FV,  McKenna WG,  Harris AL,  Bulte D,  Buffa FM,  Macpherson RE,  Higgins GS,  et al. (2023)
Supplementary Methods from Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham JL,  Chu K-Y,  Teoh E,  Chauhan J,  O’Reilly D,  Harris BHL,  Macklin PS,  Bull JA,  Green M,  Rodriguez-Berriguete G,  Prevo R,  Folkes LK,  Campo L,  Ferencz P,  Croal PL,  Flight H,  Qi C,  Holmes J,  O’Connor JPB,  Gleeson FV,  McKenna WG,  Harris AL,  Bulte D,  Buffa FM,  Macpherson RE,  Higgins GS,  et al. (2023)
Supplementary Data from Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham JL,  Chu K-Y,  Teoh E,  Chauhan J,  O’Reilly D,  Harris BHL,  Macklin PS,  Bull JA,  Green M,  Rodriguez-Berriguete G,  Prevo R,  Folkes LK,  Campo L,  Ferencz P,  Croal PL,  Flight H,  Qi C,  Holmes J,  O’Connor JPB,  Gleeson FV,  McKenna WG,  Harris AL,  Bulte D,  Buffa FM,  Macpherson RE,  Higgins GS,  et al. (2023)
Supplementary Data from Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham JL,  Chu K-Y,  Teoh E,  Chauhan J,  O’Reilly D,  Harris BHL,  Macklin PS,  Bull JA,  Green M,  Rodriguez-Berriguete G,  Prevo R,  Folkes LK,  Campo L,  Ferencz P,  Croal PL,  Flight H,  Qi C,  Holmes J,  O’Connor JPB,  Gleeson FV,  McKenna WG,  Harris AL,  Bulte D,  Buffa FM,  Macpherson RE,  Higgins GS,  et al. (2023)
Supplementary Data from Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham JL,  Chu K-Y,  Teoh E,  Chauhan J,  O’Reilly D,  Harris BHL,  Macklin PS,  Bull JA,  Green M,  Rodriguez-Berriguete G,  Prevo R,  Folkes LK,  Campo L,  Ferencz P,  Croal PL,  Flight H,  Qi C,  Holmes J,  O’Connor JPB,  Gleeson FV,  McKenna WG,  Harris AL,  Bulte D,  Buffa FM,  Macpherson RE,  Higgins GS,  et al. (2023)
Supplementary Methods from Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham JL,  Chu K-Y,  Teoh E,  Chauhan J,  O’Reilly D,  Harris BHL,  Macklin PS,  Bull JA,  Green M,  Rodriguez-Berriguete G,  Prevo R,  Folkes LK,  Campo L,  Ferencz P,  Croal PL,  Flight H,  Qi C,  Holmes J,  O’Connor JPB,  Gleeson FV,  McKenna WG,  Harris AL,  Bulte D,  Buffa FM,  Macpherson RE,  Higgins GS,  et al. (2023)
Data from Mitochondrial Inhibitor Atovaquone Increases Tumor Oxygenation and Inhibits Hypoxic Gene Expression in Patients with Non–Small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham JL,  Chu K-Y,  Teoh E,  Chauhan J,  O’Reilly D,  Harris BHL,  Macklin PS,  Bull JA,  Green M,  Rodriguez-Berriguete G,  Prevo R,  Folkes LK,  Campo L,  Ferencz P,  Croal PL,  Flight H,  Qi C,  Holmes J,  O’Connor JPB,  Gleeson FV,  McKenna WG,  Harris AL,  Bulte D,  Buffa FM,  Macpherson RE,  Higgins GS,  et al. (2023)
Chapter 9 Pancreas ectopic fat imaging-based quantification
Bagur AT,  Robson M,  Bulte D,  Brady M,  et al. (2023)
The impact of Alzheimer's disease risk factors on the pupillary light response
Sparks S,  Pinto J,  Hayes G,  Spitschan M,  Bulte DP,  et al. (2023)
The relationships between hippocampal cerebrovascular reactivity, hippocampal volume, and episodic memory in healthy ageing
Wang C,  Jobbins L,  Reid G,  Hobden G,  Mackay C,  Ebmeier KP,  Rieger S,  Patel R,  Kivimäki M,  Singh‐Manoux A,  Bulte D,  Suri S,  et al. (2023)
Investigating Alzheimer’s disease in women: is pregnancy a risk factor?
Pinto J,  Sparks S,  Hayes G,  Bulte D,  et al. (2023)
Pancreas MRI Segmentation Into Head, Body, and Tail Enables Regional Quantitative Analysis of Heterogeneous Disease.
Triay Bagur A,  Aljabar P,  Ridgway GR,  Brady M,  Bulte DP,  et al. (2022)
Using Variable Flip Angle (VFA) and Modified Look-Locker Inversion Recovery (MOLLI) T1 mapping in clinical OE-MRI.
Bluemke E,  Bertrand A,  Chu K-Y,  Syed N,  Murchison AG,  Cooke R,  Greenhalgh T,  Burns B,  Craig M,  Taylor N,  Shah K,  Gleeson F,  Bulte D,  et al. (2022)
Determination of oxygen relaxivity in oxygen nanobubbles at 3 and 7 Tesla
Bluemke E,  Young LAJ,  Owen J,  Smart S,  Kinchesh P,  Bulte DP,  Stride E,  et al. (2022)
Vascular smooth muscle cell dysfunction in neurodegeneration
Hayes G,  Pinto J,  Sparks SN,  Wang C,  Suri S,  Bulte DP,  et al. (2022)
Comparison of liver iron concentration calculated from R2* at 1.5 T and 3 T
Pickles E,  Kumar S,  Brady M,  Telford A,  Pavlides M,  Bulte D,  et al. (2022)
Oxygen-enhanced MRI and radiotherapy in patients with oropharyngeal squamous cell carcinoma.
Bluemke E,  Bertrand A,  Chu K-Y,  Syed N,  Murchison AG,  Cooke R,  Greenhalgh T,  Burns B,  Craig M,  Taylor N,  Shah K,  Gleeson F,  Bulte D,  et al. (2022)
Pancreas ectopic fat: imaging-based quantification
Triay Bagur A,  Robson M,  Bulte D,  Brady M,  et al. (2022)
Oxygen-enhanced MRI MOLLI T1 mapping during chemoradiotherapy in anal squamous cell carcinoma
Bluemke E,  Bulte D,  Bertrand A,  George B,  Cooke R,  Chu K-Y,  Durrant L,  Goh V,  Jacobs C,  Ng SM,  Strauss VY,  Hawkins MA,  Muirhead R,  et al. (2021)
Pancreas Segmentation-Derived Biomarkers: Volume and Shape Metrics in the UK Biobank Imaging Study
Bagur AT,  Ridgway G,  McGonigle J,  Brady SM,  Bulte D,  et al. (2021)
Study protocol: the Heart and Brain study
Suri S,  Bulte D,  Chiesa ST,  Ebmeier KP,  Jezzard P,  Rieger S,  Pitt J,  Griffanti L,  Okell T,  Craig M,  Chappell M,  Blockley N,  Kivimäki M,  Singh-Manoux A,  Khir A,  Hughes A,  Deanfield JE,  Jensen D,  Green S,  Segutova V,  Jansen M,  Mackay CE,  et al. (2021)
Slice-to-Volume Registration Enables Automated Pancreas MRI Quantification in UK Biobank
Bagur AT,  Aljabar P,  Arya Z,  McGonigle J,  Brady SM,  Bulte D,  et al. (2021)
Pancreas Volumetry in UK Biobank: Comparison of Models and Inference at Scale
Owler J,  Bagur AT,  Marriage S,  Arya Z,  Aljabar P,  McGonigle J,  Brady SM,  Bulte D,  et al. (2021)
Estimation of Field Inhomogeneity Map Following Magnitude-Based Ambiguity-Resolved Water-Fat Separation
Bagur AT,  McClymont D,  Hutton C,  Borghetto A,  Gyngell ML,  Aljabar P,  Robson MD,  Brady M,  Bulte DP,  et al. (2021)
Fast dynamic ventilation MRI of hyperpolarized (129) Xe using spiral imaging.
Doganay O,  Matin TN,  Mcintyre A,  Burns B,  Schulte RF,  Gleeson F,  Bulte D,  et al. (2020)
A prospective study of diffusion-weighted magnetic resonance imaging as an early prognostic biomarker in chemoradiotherapy in squamous cell carcinomas of the anus
Muirhead R,  Bulte D,  Cooke R,  Chu K-Y,  Durrant L,  Goh V,  Jacobs C,  Ng S,  Strauss V,  Virdee P,  Qi C,  Hawkins M,  et al. (2020)
Mitochondrial inhibitor atovaquone increases tumor oxygenation and inhibits hypoxic gene expression in patients with non-small cell lung cancer
Skwarski M,  McGowan D,  Belcher E,  Di Chiara F,  Stavroulias D,  McCole M,  Derham J,  Chu K-Y,  Teoh E,  Chauhan J,  O'reilly D,  Harris B,  Macklin P,  Bull J,  Green M,  Rodriguez Berriguete G,  Prevo R,  Folkes L,  Campo L,  Ferencz P,  Croal P,  Flight H,  Qi C,  Holmes J,  O'Connor J,  et al. (2020)
Cerebrovascular Reactivity Mapping Without Gas Challenges: A Methodological Guide.
Pinto J,  Bright MG,  Bulte DP,  Figueiredo P,  et al. (2020)
On the Origins of the Cerebral IVIM Signal
Hare HV,  Frost R,  Meakin JA,  Bulte DP,  et al. (2020)
Using arterial spin labelling to investigate spontaneous and evoked ongoing musculoskeletal pain
Wartolowska K,  Bulte D,  Chappell M,  Jenkinson M,  Okell T,  Webster M,  Carr A,  et al. (2019)
Magnetic resonance imaging of oxygen microbubbles
Thompson E,  Smart S,  Kinchesh P,  Bulte D,  Stride E,  et al. (2019)
A prospective study of diffusion-weighted magnetic resonance imaging for predicting outcome following chemoradiotherapy, in squamous cell carcinomas of the anus
Muirhead R,  Bulte D,  Cooke R,  Chu K-Y,  Durrant L,  Goh V,  Jacobs C,  Ng S,  Strauss VY,  Virdee P,  Qi C,  Hawkins M,  et al. (2019)
Clinical mapping of cerebrovascular reactivity using MRI: a framework for reaching consensus
Bright ,  Mazerolle EL,  Sobczyk O,  Fan AP,  van Osch MJP,  Mark CI,  Huber L,  Berman AJL,  Bulte DP,  Pike ,  Gauthier CJ,  Blockley NP,  et al. (2017)
Multiparametric measurement of cerebral physiology using calibrated fMRI
Bright ,  Croal PL,  Blockley N,  Bulte D,  et al. (2017)
Delayed ventilation assessment using fast dynamic hyperpolarised Xenon-129 magnetic resonance imaging
Gleeson F,  Bulte D,  Doganay O,  Matin T,  Rahman N,  Chen M,  McIntyre A,  et al. (2017)
Monitoring cardiac and respiratory physiology during FMRI
Bulte D,  Wartolowska K,  et al. (2016)
Data acquired to investigate new approaches to cerebrovascular reactivity mapping using MRI
Blockley NP,  Harkin JW,  Stone AJ,  Bulte DP,  et al. (2016)
Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele.
Suri S,  Mackay CE,  Kelly ME,  Germuska M,  Tunbridge EM,  Frisoni GB,  Frisoni GB,  Matthews PM,  Ebmeier KP,  Bulte DP,  Filippini N,  et al. (2015)
Investigating the field-dependence of the Davis model: Calibrated fMRI at 1.5, 3 and 7 T
Hare HV,  Blockley N,  Gardener AG,  Clare S,  Bulte D,  et al. (2015)
Sources of systematic error in calibrated BOLD based mapping of baseline oxygen extraction fraction
Blockley N,  Griffeth VEM,  Stone AJ,  Hare HV,  Bulte DP,  et al. (2015)
Evaluating cerebrovascular reactivity dynamics through a Bayesian inference approach
Pinto J,  Craig M,  Croal P,  Blockley N,  Chappell M,  Bulte D,  et al. (2015)
The influence of noise on BOLD-mediated vessel size imaging analysis methods.
Germuska MA,  Meakin JA,  Bulte DP,  et al. (2013)
The influence of noise on BOLD-mediated vessel size imaging analysis methods
Germuska MA,  Meakin JA,  Bulte DP,  et al. (2013)
Quantitative measurement of cerebral physiology using respiratory-calibrated MRI.
Bulte DP,  Kelly M,  Germuska M,  Xie J,  Chappell MA,  Okell TW,  Bright MG,  Jezzard P,  et al. (2012)
Quantitative measurement of cerebral physiology using respiratory-calibrated MRI
Bulte DP,  Kelly ME,  Germuska M,  Xie J,  Chappell MA,  Okell TW,  Bright MG,  Jezzard P,  et al. (2012)
The effect of basal vasodilation on hypercapnic and hypocapnic reactivity measured using magnetic resonance imaging.
Bright MG,  Donahue MJ,  Duyn JH,  Jezzard P,  Bulte DP,  et al. (2011)
Measurement of relative cerebral blood volume using BOLD contrast and mild hypoxic hypoxia.
Wise RG,  Pattinson KTS,  Bulte DP,  Rogers R,  Tracey I,  Matthews PM,  Jezzard P,  et al. (2010)
Quantitative fMRI using hyperoxia calibration: reproducibility during a cognitive Stroop task.
Goodwin JA,  Vidyasagar R,  Balanos GM,  Bulte D,  Parkes LM,  et al. (2009)
Hyperoxia and Functional MRI.
Bulte D,  et al. (2009)
Evidence for a vascular contribution to diffusion FMRI at high b value.
Miller KL,  Bulte DP,  Devlin H,  Robson MD,  Wise RG,  Woolrich MW,  Jezzard P,  Behrens TEJ,  et al. (2007)
Dynamic forcing of end-tidal carbon dioxide and oxygen applied to functional magnetic resonance imaging.
Wise RG,  Pattinson KTS,  Bulte DP,  Chiarelli PA,  Mayhew SD,  Balanos GM,  O'Connor DF,  Pragnell TR,  Robbins PA,  Tracey I,  Jezzard P,  et al. (2007)
Flow-metabolism coupling in human visual, motor, and supplementary motor areas assessed by magnetic resonance imaging.
Chiarelli PA,  Bulte DP,  Gallichan D,  Piechnik SK,  Wise R,  Jezzard P,  et al. (2007)
Measurement of cerebral blood volume in humans using hyperoxic MRI contrast.
Bulte D,  Chiarelli P,  Wise R,  Jezzard P,  et al. (2007)
A calibration method for quantitative BOLD fMRI based on hyperoxia.
Chiarelli PA,  Bulte DP,  Wise R,  Gallichan D,  Jezzard P,  et al. (2007)
Cerebral perfusion response to hyperoxia.
Bulte DP,  Chiarelli PA,  Wise RG,  Jezzard P,  et al. (2007)
Sources of systematic bias in hypercapnia-calibrated functional MRI estimation of oxygen metabolism.
Chiarelli PA,  Bulte DP,  Piechnik S,  Jezzard P,  et al. (2007)
Vasomodulation of skeletal muscle BOLD signal.
Bulte DP,  Alfonsi J,  Bells S,  Noseworthy MD,  et al. (2006)
Phase-retardation effects at radio frequencies in flat-plate conductors
Bulte DP,  Forbes LK,  Crozier S,  et al. (2004)
BOLD magnetic resonance imaging of skeletal muscle.
Noseworthy MD,  Bulte DP,  Alfonsi J,  et al. (2003)
Origins of the magnetomechanical effect
Bulte DP,  Langman RA,  et al. (2002)
Comparison of the normal and initial induction curves
Bulte D,  Langman R,  et al. (2001)
Tunnelling of a Molecule
Jarvis PD,  Bulte D,  et al. (1998)
A method and apparatus of measuring the stress or strain of a portion of a ferromagnetic member
Bulte DP,  et al. ()
Repurposing Atovaquone as a Tumor Hypoxia Modifier: A Window of Opportunity Study in Patients with Resectable Non-small Cell Lung Cancer
Skwarski M,  McGowan DR,  Belcher E,  Di Chiara F,  Stavroulias D,  Prevo R,  Macklin PS,  Chauhan J,  O'Reilly D,  Green M,  Ferencz P,  Rodriguez-Berriguete G,  Flight H,  Qi C,  Holmes J,  Buffa F,  McCole M,  Bulte D,  Macpherson R,  Higgins GS,  et al. ()
A novel "chirp" stimulus protocol for assessing photoreceptor function across wavelength, time, and contrast
Martin J,  Bulte D,  Spitschan M,  et al. ()
Bayesian Modelling Approaches for Breath-Hold Induced Cerebrovascular Reactivity
Hayes G,  Bulte DP,  Moia S,  Craig M,  Chappell M,  Uruñuela E,  Sparks S,  Caballero-Gaudes C,  Pinto J,  et al. ()
SENSE and Compressed SENSE chemical shift encoded multi-gradient echo for T2* quantification in the liver
Pickles E,  Connell J,  Kin S,  Telford A,  Kazimianec A,  Brady M,  Bulte D,  Chong OF,  Choo HJ,  Ithnin SB,  Chang JPE,  Lee GH,  De Roza MA,  Ong KK,  Wee SY-M,  Tan KT,  Tan NC,  Toh HC,  Wong YJ,  Yang WL,  Yeap XY,  Chua CME,  Chua JSS,  Goh JSQ,  Lai LSH,  Sim YK,  Chow PKH,  et al. ()
Bayesian and lagged general linear modelling strategies in breath-hold induced cerebrovascular reactivity mapping with muti-echo BOLD fMRI
Hayes G,  Pinto J,  Moia S,  Craig M,  Chappell M,  Caballero-Gaudes C,  Bulte D,  et al. ()
Development of Hepatocellular Carcinoma phantom and its use for assessing R2* mapping sequences for detecting iron sparing
Pickles E,  Cox E,  Telford A,  Mozes F,  Belsley G,  Tunnicliffe E,  Brady M,  Pavlides M,  Bulte D,  Francis S,  et al. ()
PDFF and R2* Reconstruction Error Mapping using Cramér-Rao Lower Bounds for Quality Assessment In-Vivo
Bagur AT,  Aljabar P,  Robson M,  Brady M,  Bulte D,  et al. ()
Bayesian Networks Reveal the Interplay Between Quantitative Liver MRI Metrics
Wang Y-C,  Salvati R,  Connell J,  Van Zijl N,  Waddell T,  Bulte D,  Brady M,  et al. ()