Professor
Constantin Coussios
OBE FREng
Director, Institute of Biomedical Engineering
Statutory Chair of Biomedical Engineering
Professorial Fellow of Magdalen College
Cavitation-mediated extravasation and transtumoral drug delivery by microstreaming: What role do the gas nuclei and the physical properties of the therapeutic play?
Coussios C,  Myers R,  Kwan J,  Lea-Banks H,  Mo S,  Grundy M,  Mannaris C,  Duffy M,  Paverd C,  Carugo D,  Coviello C,  Stride E,  Carlisle R,  et al. (2023)
Ultrasound-enhanced thrombolysis: Mechanistic observations
de Saint Victor M,  Carugo D,  Coussios C,  Stride EP,  et al. (2023)
Normothermic Machine Perfusion of Donor Livers for Transplantation in the United States: A Randomized Controlled Trial.
Chapman WC,  Barbas AS,  D'Alessandro AM,  Vianna R,  Kubal CA,  Abt P,  Sonnenday C,  Barth R,  Alvarez-Casas J,  Yersiz H,  Eckhoff D,  Cannon R,  Genyk Y,  Sher L,  Singer A,  Feng S,  Roll G,  Cohen A,  Doyle MB,  Sudan DL,  Al-Adra D,  Khan A,  Subramanian V,  Abraham N,  Olthoff K,  Tekin A,  Berg L,  Coussios C,  Morris C,  Randle L,  Friend P,  Knechtle SJ,  et al. (2023)
Cavitation-Mediated Immunomodulation and Its Use with Checkpoint Inhibitors.
Maardalen M,  Carlisle R,  Coussios C,  et al. (2023)
Diffusion-limited O2 release in human kidneys perfused with stored blood
Dumbill R,  Rabcuka J,  Knight S,  Hunter J,  Fallon J,  Voyce D,  Barrett J,  Ellen M,  Weissenbacher A,  Kurniawan T,  Blonski S,  Korczyk P,  Ploeg R,  Coussios C,  Friend P,  Swietach P,  et al. (2023)
Cavitation‐mediated Transcutaneous Delivery of Protein and Nucleotide‐based Antigen for Rapid High‐level Immune Responses
Hettinga JK,  Lyons B,  Balkaran J,  Rijal P,  Dunn‐Lawless D,  Caproni L,  Gray M,  Suslick KS,  Coussios CC,  Carlisle RC,  et al. (2023)
Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound
Spiers L,  Gray M,  Lyon P,  Sivakumar S,  Bekkali N,  Scott S,  Collins L,  Carlisle R,  Wu F,  Middleton M,  Coussios C-C,  et al. (2023)
Hemodynamics and metabolic parameters in normothermic kidney preservation are linked with donor factors, perfusate cells, and cytokines
Weissenbacher A,  Stone JP,  Lo Faro ML,  Hunter JP,  Ploeg RJ,  Coussios CC,  Fildes JE,  Friend PJ,  et al. (2022)
Thermosensitive liposomes: a promising step toward localised chemotherapy
Chaudhry M,  Lyon P,  Coussios C,  Carlisle R,  et al. (2022)
Preclinical safety and feasibility of in situ Isolated Normothermic Liver Chemoperfusion (INLiC)
Clark T,  Ebeling G,  Baù L,  Voyce D,  Ogbemudia A,  Coussios C,  Friend P,  et al. (2022)
Improved therapeutic antibody delivery to xenograft tumors using cavitation nucleated by gas-entrapping nanoparticles
Grundy M,  Bau L,  Hill C,  Paverd C,  Mannaris C,  Kwan J,  Crake C,  Coviello C,  Coussios C,  Carlisle R,  et al. (2021)
Large-volume hyperthermia for safe and cost-effective targeted drug delivery using a clinical ultrasound-guided focused ultrasound device
Lyon PC,  Mannaris C,  Gray M,  Carlisle R,  Gleeson FV,  Cranston D,  Wu F,  Coussios CC,  et al. (2021)
Quantifying cell death induced by doxorubicin, hyperthermia or HIFU ablation with flow cytometry
Lyon P,  Suomi V,  Jakeman P,  Campo L,  Coussios C,  Carlisle R,  et al. (2021)
Polymer stealthing and mucin-1 retargeting for enhanced pharmacokinetics of an oncolytic vaccinia virus
Hill C,  Grundy M,  Bau L,  Wallington S,  Balkaran J,  Ramos V,  Fisher K,  Seymour L,  Coussios C-C,  Carlisle R,  et al. (2021)
Noninvasive assessment of steatosis and viability of cold-stored human liver grafts by MRI
Young L,  Ceresa CDL,  Mózes FE,  Ellis J,  Valkovič L,  Colling R,  Coussios C-C,  Friend PJ,  Rodgers CT,  et al. (2021)
Predicting clinical pharmacokinetics and toxicity of current and emerging oncology therapeutics by normothermic perfusion of isolated human-sized organs.
Clark T,  Bau L,  Dengu F,  Voyce D,  Carlisle R,  Friend P,  Coussios C,  et al. (2021)
Preclinical feasibility of in situ isolated normothermic liver chemoperfusion
Clark T,  Ebeling G,  Voyce D,  Bau L,  Coussios C,  Friend P,  et al. (2021)
Urine Recirculation Improves Hemodynamics and Enhances Function in Normothermic Kidney Perfusion
Weissenbacher A,  Voyce D,  Ceresa CDL,  Soares MF,  Roberts IS,  Hunter JP,  Cook A,  Ploeg RJ,  Coussios CC,  Friend PJ,  et al. (2020)
Urine recirculation improves hemodynamics and enhances function in normothermic kidney perfusion
Weissenbacher A,  Voyce D,  Ceresa CDL,  Soares MF,  Roberts IS,  Hunter JP,  Cook A,  Ploeg RJ,  Coussios CC,  Friend PJ,  et al. (2020)
Dual array passive acoustic mapping for cavitation imaging with enhanced 2-D resolution
Gray M,  Elbes D,  Paverd C,  Lyka E,  Coviello C,  Cleveland RO,  Coussios C-C,  et al. (2020)
Urine recirculation prolongs normothermic kidney perfusion via more optimal metabolic homeostasis – a proteomics study
Weissenbacher A,  Huang H,  Surik T,  Lo Faro ML,  Ploeg RJ,  Coussios CC,  Friend PJ,  Kessler BM,  et al. (2020)
Arterial Flow, Lactate and NGAL as a Decision Making Trinity in Normothermic Kidney Preservation
Weissenbacher A,  Lo Faro ML,  Coussios CC,  Friend PJ,  et al. (2020)
Focused ultrasound hyperthermia for targeted drug release from thermosensitive liposomes: results from a phase I trial
Gray MD,  Lyon P,  Mannaris C,  Folkes L,  Stratford M,  Campo L,  Chung DYF,  Scott S,  Anderson M,  Goldin R,  Carlisle R,  Wu F,  Middleton M,  Gleeson F,  Coussios C,  et al. (2019)
Passive acoustic mapping of extravasation following ultrasound-enhanced drug delivery
Paverd C,  Lyka E,  Elbes D,  Coussios C,  et al. (2019)
Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial.
Lyon PC,  Mannaris C,  Folkes LK,  Stratford M,  Campo L,  Chung DYF,  Scott S,  Anderson M,  Goldin R,  Carlisle R,  Wu F,  Middleton MARK,  Gleeson FV,  Coussios CC,  et al. (2019)
Microbubbles, nanodroplets and gas-stabilizing solid particles for ultrasound-mediated extravasation of unencapsulated drugs: an exposure parameter optimization study.
Mannaris C,  Bau L,  Grundy M,  Gray M,  Lea-Banks H,  Seth A,  Teo B,  Carlisle R,  Stride E,  Coussios C,  et al. (2019)
Sonothrombolysis with magnetically targeted microbubbles
de Saint Victor M,  Barnsley L,  Carugo D,  Owen J,  Coussios C,  Stride E,  et al. (2019)
Nucleation, mapping and control of cavitation for drug delivery
Stride E,  Coussios C,  et al. (2019)
Delivering focused ultrasound to intervertebral discs using time-reversal
Qiao S,  Elbes D,  Boubriak O,  Urban J,  Coussios C-C,  Cleveland R,  et al. (2019)
Transient cold storage prior to normothermic liver perfusion may facilitate adoption of a novel technology
Ceresa C,  Nasralla D,  Watson CJE,  Butler AJ,  Coussios CC,  Crick K,  Hodson L,  Imber C,  Jassem W,  Knight S,  Mergental H,  Ploeg R,  Pollok JM,  Quaglia A,  Shapiro AMJ,  Weissenbacher A,  Friend P,  et al. (2019)
Proteomics Reveals Molecular Window and Metabolism of Normothermically Perfused Human Kidneys.
Weissenbacher A,  Huang H,  Thorne A,  Lo Faro LM,  Hunter J,  Ploeg R,  Coussios CC,  Friend PJ,  Kessler B,  et al. (2019)
PROTEOMICS REVEALS MOLECULAR WINDOW AND METABOLISM OF NORMOTHERMICALLY PERFUSED HUMAN KIDNEYS
Weissenbacher A,  Huang H,  Lo Faro L,  Hunter J,  Ploeg R,  Coussios C,  Friend P,  Kessler B,  et al. (2019)
URINE RECIRCULATION IMPROVES HAEMODYNAMICS AND ENHANCES FUNCTION IN NORMOTHERMIC KIDNEY PERFUSION
Weissenbacher A,  Ceresa C,  Hunter J,  Voyce D,  Soares M,  Ploeg R,  Coussios C,  Friend P,  et al. (2019)
URINE RECIRCULATION IMPROVES HAEMODYNAMICS AND ENHANCES FUNCTION IN NORMOTHERMIC KIDNEY PERFUSION
Weissenbacher A,  Friend PJ,  Coussios CC,  et al. (2019)
Novel approaches in optimising steatotic livers for transplantation
Ceresa C,  Nasralla D,  Cornfield T,  Clark A,  Hook P,  Young L,  Barnes J,  Sankaran V,  Weissenbacher A,  Wills Q,  Sanna F,  Coussios C,  Hodson L,  Friend P,  et al. (2019)
Diffraction effects and compensation in passive acoustic mapping
Gray MD,  Lyka E,  Coussios C,  et al. (2018)
The case for normothermic machine perfusion in liver transplantation
Ceresa C,  Nasralla D,  Coussios C,  Friend P,  et al. (2018)
Ultrasound-mediated cavitation does not decrease the activity of small molecule, antibody or viral-based medicines
Myers R,  Grundy M,  Rowe C,  Coviello CM,  Bau L,  Erbs P,  Foloppe J,  Balloul J-M,  Story C,  Coussios C,  Carlisle R,  et al. (2018)
A randomized trial of normothermic preservation in liver transplantation
Nasralla D,  Coussios CC,  Mergental H,  Akhtar MZ,  Butler A,  Ceresa C,  Chiocchia V,  Dutton SJ,  García-Valdecasas JC,  Heaton N,  Imber C,  Jassem W,  Jochmans I,  Karani J,  Knight S,  Kocabayoglu P,  Malagò M,  Mirza D,  Morris P,  Pallan A,  Paul A,  Pavel M,  Perera T,  Pirenne J,  Ravikumar R,  et al. (2018)
Gas-stabilizing gold nanocones for acoustically mediated drug delivery
Mannaris C,  Teo BM,  Seth A,  Bau L,  Coussios C,  Stride E,  et al. (2018)
Twenty-four-hour normothermic perfusion of discarded human kidneys with urine recirculation
Weissenbacher A,  Lo Faro L,  Boubriak O,  Soares MF,  Roberts I,  Hunter J,  Voyce D,  Mikov N,  Cook A,  Ploeg R,  Coussios C,  Friend P,  et al. (2018)
Layered acoustofluidic resonators for the study of the physical and biological effects of acoustic cavitation
Pereno V,  Aron MM,  Vince OF,  Mannaris C,  Seth A,  de Saint Victor M,  Lajoinie G,  Versluis M,  Coussios C-C,  Carugo D,  Stride EPJ,  et al. (2018)
Passive acoustic mapping using data-adaptive beamforming based on higher-order statistics
Lyka E,  Coviello CM,  Paverd C,  Gray M,  Coussios C,  et al. (2018)
The effect of normothermic machine perfusion after cold storage in liver transplantation: a multicentre prospective clinical trial
Ceresa C,  Nasralla D,  Watson C,  Butler A,  Crick K,  Imber C,  Pollok J,  Jassem W,  Mergental H,  Knight S,  Ploeg R,  Coussios C,  Friend P,  et al. (2018)
Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial
Lyon P,  Gray ,  Mannaris C,  Folkes L,  Stratford M,  Campo L,  Chung DYF,  Scott S,  Anderson M,  Goldin R,  Carlisle R,  Wu F,  Middleton M,  Gleeson F,  Coussios C,  et al. (2018)
Long-term radiological and histological outcomes following selective internal radiation therapy to liver metastases from breast cancer
Lyon P,  Winter H,  Herbschleb K,  Campo L,  Carlisle R,  Wu F,  Goldin R,  Coussios C,  Middleton M,  Gleeson F,  Boardman P,  Sharma R,  et al. (2018)
Exploring the Structural and Functional Effects of Normothermic Machine Perfusion and DeFatting Interventions on Human Steatotic Livers
Ceresa C,  Nasralla D,  Cornfield T,  Clark A,  Hook P,  Young L,  Coussios C,  Hodson L,  Friend PJ,  et al. (2018)
Patient Specific Simulation of HIFU Kidney Tumour Ablation.
Magda Abbas A,  Constatin-Coussios C,  Robin Cleveland O,  et al. (2018)
Normothermic machine perfusion (NMP) inhibits proinflammatory responses in the liver and promotes regeneration
Jassem W,  Xystrakis E,  Ghnewa YG,  Yuksel M,  Pop O,  Martinez-Llordella M,  Jabri Y,  Huang X,  Lozano JJ,  Quaglia A,  Sanchez-Fueyo A,  Coussios C,  Rela M,  Friend P,  Heaton N,  Ma Y,  et al. (2018)
Preliminary Single-Center Canadian Experience of Human Normothermic Ex Vivo Liver Perfusion: Results of a Clinical Trial.
Bral M,  Gala-Lopez B,  Bigam D,  Kneteman N,  Malcolm A,  Livingstone S,  Andres A,  Emamaullee J,  Russell L,  Coussios C,  West LJ,  Friend PJ,  Shapiro AMJ,  et al. (2017)
The 24-hour normothermic machine perfusion of discarded human liver grafts.
Vogel T,  Brockmann JG,  Quaglia A,  Morovat A,  Jassem W,  Heaton ND,  Coussios CC,  Friend PJ,  et al. (2017)
Liver splitting during normothermic organ preservation.
Brockmann JG,  Vogel T,  Coussios C,  Friend PJ,  et al. (2017)
Outcomes from a Multinational Randomised Controlled Trial Comparing Normothermic Machine Perfusion with Static Cold Storage in Human Liver Transplantation
Nasralla D,  Ploeg R,  Coussios C,  Friend P,  et al. (2017)
Outcomes from a Multinational Randomised Controlled Trial Comparing Normothermic Machine Perfusion with Static Cold Storage in Human Liver Transplantation
Nasralla D,  Ploeg R,  Coussios C,  Friend P,  et al. (2017)
Development of an Automatic Regulated Normothermic Kidney Preservation Device for Long-Term Organ Perfusion
Weissenbacher A,  Boubriak O,  Lo Faro L,  Ploeg R,  Hunter J,  Voyce D,  Mikov N,  Cook A,  Coussios C,  Friend P,  et al. (2017)
Magnetic targeting to enhance microbubble delivery in an occluded microarterial bifurcation
de Saint Victor M,  Carugo D,  Barnsley LC,  Owen J,  Coussios CC,  Stride E,  et al. (2017)
The use of normothermic machine perfusion in liver viability assessment - can we predict post-transplant outcomes?
Ceresa C,  Nasralla D,  Morovat A,  Mergental H,  Jassem W,  Butler A,  Imber C,  Knight S,  Coussios C,  Ploeg R,  Friend P,  et al. (2017)
Effect of normothermic machine perfusion on outcomes after steatotic liver transplantation: a first assessment
Ceresa C,  Nasralla D,  Neil D,  Mergental H,  Jassem W,  Butler A,  Imber C,  Hodson L,  Weissenbacher A,  Coussios C,  Ploeg R,  Friend P,  et al. (2017)
DEVELOPMENT OF AN AUTOMATIC REGULATED NORMOTHERMIC KIDNEY PRESERVATION DEVICE FOR LONG-TERM PERFUSION
Weissenbacher A,  Lo Faro L,  Boubriak O,  Hunter J,  Ploeg R,  Mikov N,  Cook A,  Voyce D,  Coussios C,  Friend P,  et al. (2017)
A histological and biochemical assessment of steatotic livers undergoing normothermic machine perfusion
Ceresa C,  Nasralla D,  Neil D,  Mergental H,  Jassem W,  Butler A,  Imber C,  Barrett A,  Clark A,  Coussios C,  Ploeg R,  Hodson L,  Friend P,  et al. (2017)
THE IMMUNOLOGICAL EFFECTS OF NORMOTHERMIC MACHINE PERFUSION OF THE LIVER
Nasralla D,  Critchley W,  Coussios C,  Ploeg R,  Friend P,  Fildes J,  et al. (2017)
Successful transplantation of porcine liver grafts following 48-hour normothermic preservation
Vogel T,  Brockmann JG,  Pigott D,  Neil DAH,  Muthusamy AS,  Coussios C,  Friend P,  et al. (2017)
Ultrasound-mediated cavitation-enhanced extravasation of mesoporous silica nanoparticles for controlled-release drug delivery
Paris JL,  Mannaris C,  Victoria Cabanas M,  Carlisle R,  Manzano M,  Vallet-Regi M,  Coussios C,  et al. (2017)
Magnetic targeting to enhance microbubble delivery in an occluded micro arterial bifurcation
de Saint Victor M,  Carugo D,  Barnsley LC,  Owen J,  Coussios CC,  Stride E,  et al. (2017)
Liver Transplantation After Ex Vivo Normothermic Machine Preservation: A Phase 1 (First-in-Man) Clinical Trial.
Ravikumar R,  Jassem W,  Mergental H,  Heaton N,  Mirza D,  Perera MTPR,  Quaglia A,  Holroyd D,  Vogel T,  Coussios CC,  Friend PJ,  et al. (2016)
Correction to ‘Magnetic targeting of Microbubbles against Physiologically relevant flow conditions’(Interface Focus 5, 20150001, 2015, 10.1098/rsfs.2015.0001)
Owen J,  Rademeyer P,  Chung D,  Cheng Q,  Holroyd D,  Coussios C,  Friend P,  Pankhurst QA,  Stride E,  et al. (2016)
In vitro methods to study bubble-cell interactions: Fundamentals and therapeutic applications.
Lajoinie G,  De Cock I,  Coussios CC,  Lentacker I,  Le Gac S,  Stride E,  Versluis M,  et al. (2016)
TARDOX: Safety and Feasibility of Targeted Delivery of Lyso-Thermosensitive Liposomal Doxorubicin (ThermoDox®) By Focused-Ultrasound Hyperthermia for Liver Tumours
Odondi LET,  Lyon PC,  Boyle LF,  Wu F,  Middleton M,  Gleeson F,  Coussios C,  et al. (2016)
Polymeric cups for cavitation mediated delivery of oncolytic vaccinia virus
Myers R,  Coviello C,  Erbs P,  Foloppe J,  Rowe C,  Kwan J,  Crake C,  Finn S,  Jackson E,  Balloul J-M,  Story C,  Coussios C,  Carlisle R,  et al. (2016)
Enhancement and passive acoustic mapping of cavitation from fluorescently tagged magnetic resonance-visible magnetic microbubbles in vivo.
Crake C,  Owen J,  Smart S,  Coviello C,  Coussios C-C,  Carlisle R,  Stride E,  et al. (2016)
The effect of particle density on ultrasound-mediated transport of nanoparticles
Lea-Banks H,  Teo B,  Stride E,  Coussios CC,  et al. (2016)
Normothermic machine perfusion of deceased donor liver grafts is associated with improved postreperfusion hemodynamics
Angelico R,  Perera MTPR,  Ravikumar R,  Holroyd D,  Coussios C,  Mergental H,  Iqbal A,  Cilliers H,  Muiesan P,  Friend P,  Mirza DF,  et al. (2016)
Ultrahigh-Speed Dynamics of Micrometer-Scale Inertial Cavitation from Nanoparticles
Kwan JJ,  Lajoinie G,  de Jong N,  Stride E,  Versluis M,  Coussios CC,  et al. (2016)
Correction to 'Magnetic targeting of microbubbles against physiologically relevant flow conditions'.
Owen J,  Rademeyer P,  Chung D,  Cheng Q,  Holroyd D,  Coussios C,  Friend P,  Pankhurst QA,  Stride E,  et al. (2016)
Ex vivo perfusion of human livers induces leukocyte mobilisation
Nasralla D,  Critchley W,  Ball A,  Edge R,  Amin K,  Coussios C,  Friend P,  Fildes J,  et al. (2016)
Surgical experience of normothermic machine perfusion in human liver transplantation
Nasralla D,  Mergental H,  Perera T,  Muiesan P,  Weissenbacher A,  Ceresa C,  Jassem W,  Coussios C,  Friend P,  et al. (2016)
Tips for a successful normothermic liver perfusion
Nasralla D,  Mergental H,  Perera T,  Jassem W,  Weissenbacher A,  Ceresa C,  Morris C,  Russell L,  Coussios C,  Friend P,  et al. (2016)
Passive acoustic mapping of magnetic microbubbles for cavitation enhancement and localization.
Crake C,  Victor MDS,  Owen J,  Coviello C,  Collin J,  Coussios C-C,  Stride E,  et al. (2015)
Quantification of ultrasonic texture intra-heterogeneity via volumetric stochastic modeling for tissue characterization.
Al-Kadi OS,  Chung DYF,  Carlisle RC,  Coussios CC,  Noble JA,  et al. (2015)
Oxygen carrying microbubbles for enhanced sonodynamic therapy of hypoxic tumours.
McEwan C,  Owen J,  Stride E,  Fowley C,  Nesbitt H,  Cochrane D,  Coussios CC,  Borden M,  Nomikou N,  McHale AP,  Callan JF,  et al. (2015)
Quantification of ultrasonic texture intra-heterogeneity via volumetric stochastic modeling for tissue characterization
Al-Kadi OS,  Chung DYF,  Carlisle RC,  Coussios CC,  Noble JA,  et al. (2015)
Cavitation-enhanced delivery of insulin in agar and porcine models of human skin.
Feiszthuber H,  Bhatnagar S,  Gyöngy M,  Coussios C-C,  et al. (2015)
Increasing the density of nanomedicines improves their ultrasound-mediated delivery to tumours
Mo S,  Carlisle R,  Laga R,  Myers R,  Graham S,  Cawood R,  Ulbrich K,  Seymour L,  Coussios C,  et al. (2015)
Passive acoustic mapping utilizing optimal beamforming in ultrasound therapy monitoring.
Coviello C,  Kozick R,  Choi J,  Gyöngy M,  Jensen C,  Smith PP,  Coussios C-C,  et al. (2015)
Nanoparticle‐Loaded Protein–Polymer Nanodroplets for Improved Stability and Conversion Efficiency in Ultrasound Imaging and Drug Delivery
Lee JY,  Carugo D,  Crake C,  Owen J,  De Saint Victor M,  Seth A,  Coussios C,  Stride E,  et al. (2015)
Ultrasound-propelled nanocups for drug delivery
Kwan J,  Myers R,  Coussios C,  al. E,  et al. (2015)
Magnetic targeting of microbubbles against physiologically relevant flow conditions
Owen J,  Rademeyer P,  Chung D,  Cheng Q,  Holroyd D,  Coussios C,  Friend P,  Pankhurst QA,  Stride E,  et al. (2015)
Ultrasound-induced inertial cavitation from gas-stabilizing nanoparticles.
Kwan JJ,  Graham S,  Myers R,  Carlisle R,  Stride E,  Coussios CC,  et al. (2015)
Nanoparticle-Loaded Protein-Polymer Nanodroplets for Improved Stability and Conversion Efficiency in Ultrasound Imaging and Drug Delivery
Lee JY,  Carugo D,  Crake C,  Owen J,  De Saint Victor M,  Seth A,  Coussios C,  Stride E,  et al. (2015)
Simulation of nonlinear propagation of biomedical ultrasound using PZFlex and the KZK Texas code
Qiao S,  Jackson E,  Coussios C-C,  Cleveland R,  et al. (2015)
DETERIORATION OF MITOCHONDRIAL FUNCTION IS THE KEY MECHANISM RESPONSIBLE FOR HEPATIC INJURY IN DCD LIVERS
Nasralla D,  Roy D,  Morten K,  Morovat R,  Coussios C,  Friend P,  et al. (2015)
NORMOTHERMIC REGIONAL PERFUSION RESUSCITATES DCD LIVERS BY MITOCHONDRIAL PROTECTION
Roy D,  Jamieson R,  Morten K,  Morovat A,  Coussios C,  Friend P,  et al. (2015)
SURGICAL EXPERIENCE WITH NORMOTHERMIC MACHINE PERFUSION IN HUMAN LIVER TRANSPLANTATION
Nasralla D,  Weissenbacher A,  Mergental H,  Jassem W,  Coussios C,  Friend P,  et al. (2015)
Hepatic T Cells Derived from Normothemic Machine Perfused Grafts Contained More Regulatory T Cells and Fewer Proinflammatory Cytokines Producing T Cells Than Those from Cold Storage Grafts
Huang X,  Ravikumar R,  Coussios C,  Srinivasan P,  Heaton N,  Friend P,  Jassem W,  Ma Y,  et al. (2015)
Normothemic Machine Perfusion of Liver Grafts Promotes Liver Regeneration and Inhibits Tissue Inflammation
Xystrakis E,  Lozano J,  Danger R,  Martinez-Llordella M,  Srinivasan P,  Heaton N,  Coussios C,  Sanchez-Fueyo A,  Ma Y,  Jassem W,  et al. (2015)
FROM DETECTING RED BLOOD CELLS TO MAPPING ACOUSTIC BUBBLES: THE LESSER-KNOWN FFOWCS WILLIAMS LEGACY
Coussios C-C,  et al. (2015)
Nanoparticle-loaded protein-polymer nanodroplets for improved stability and conversion efficiency in ultrasound imaging and drug delivery
Victor M-ADMDS,  Crake C,  Owen J,  Seth A,  Lee J,  Stride E,  Carugo D,  Victor M-ADMDS,  et al. (2015)
Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes.
Graham SM,  Carlisle R,  Choi JJ,  Stevenson M,  Shah AR,  Myers RS,  Fisher K,  Peregrino M-B,  Seymour L,  Coussios CC,  et al. (2014)
Properties, characteristics and applications of microbubbles for sonothrombolysis.
de Saint Victor M,  Crake C,  Coussios C-C,  Stride E,  et al. (2014)
Exploitation of acoustic cavitation-induced microstreaming to enhance molecular transport.
Bhatnagar S,  Schiffter H,  Coussios C-C,  et al. (2014)
Exploitation of acoustic cavitation-induced microstreaming to enhance molecular transport
Bhatnagar S,  Schiffter H,  Coussios CC,  et al. (2014)
Normothermic Perfusion of Discarded Human Pancreases.
Ravikumar R,  Coussios C,  Friend P,  et al. (2014)
Non-invasive and real-time passive acoustic mapping of ultrasound-mediated drug delivery.
Choi JJ,  Carlisle RC,  Coviello C,  Seymour L,  Coussios C-C,  et al. (2014)
Normothermic Perfusion of Discarded Human Pancreases
Ravikumar R,  Coussios C,  Friend P,  et al. (2014)
Simulations of ultrasound propagation in a spinal structure.
Qiao S,  Coussios CC,  Cleveland RO,  et al. (2014)
Human Liver Transplantation Using Normothermic Machine Preservation.
Ravikumar R,  Coussios CC,  Holroyd D,  Heaton N,  Friend PJ,  Jassem W,  et al. (2014)
Improving Delivery of Oncolytic Viruses to Solid Tumours
Carlisle R,  Mo S,  Myers R,  Graham S,  Laga R,  Ulbrich K,  Coussios C,  Seymour L,  et al. (2014)
Targeting of liposomes via PSGL1 for enhanced tumor accumulation.
Carlisle R,  Seymour LW,  Coussios CC,  et al. (2013)
A non-exothermic cell-embedding tissue-mimicking material for studies of ultrasound-induced hyperthermia and drug release.
Mylonopoulou E,  Bazán-Peregrino M,  Arvanitis CD,  Coussios CC,  et al. (2013)
Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound.
Bazan-Peregrino M,  Rifai B,  Carlisle RC,  Choi J,  Arvanitis CD,  Seymour LW,  Coussios CC,  et al. (2013)
Inertial cavitation at the nanoscale.
Kwan JJ,  Graham S,  Coussios C,  et al. (2013)
Passive acoustic mapping of magnetic microbubbles in an in vitro flow model.
Crake C,  de Saint Victor M,  Coviello C,  Owen J,  Coussios CC,  Stride E,  et al. (2013)
Real-time three-dimensional passive cavitation detection for clinical high intensity focused ultrasound systems.
Collin J,  Coviello C,  Lyka E,  Leslie T,  Coussios C,  et al. (2013)
Coating of adenovirus type 5 with cleavable PEGylated gold nanoparticles for enhanced protection and circulation
Mo S,  Carlisle R,  Coussios C-C,  Seymour L,  et al. (2013)
Passive acoustic mapping using optimal beamforming for real-time monitoring of ultrasound therapy
Coviello C,  Kozick RJ,  Choi JJ,  Gyöngy M,  Collin J,  Jensen C,  Smith PP,  Coussios CC,  et al. (2013)
Passive acoustic mapping of magnetic microbubbles in an in vitro flow model
Crake C,  De Saint Victor M,  Coviello C,  Owen J,  Coussios CC,  Stride E,  et al. (2013)
Real-time three-dimensional passive cavitation detection for clinical high intensity focussed ultrasound systems
Collin J,  Coviello C,  Lyka E,  Leslie T,  Coussios CC,  et al. (2013)
Inertial cavitation at the nanoscale
Kwan JJ,  Graham S,  Coussios CC,  et al. (2013)
Calibration of ultrasound backscatter temperature imaging for high-intensity focused ultrasound treatment planning.
Civale J,  Rivens I,  Ter Haar G,  Morris H,  Coussios C,  Friend P,  Bamber J,  et al. (2013)
Calibration of ultrasound backscatter temperature imaging for high-intensity focused ultrasound treatment planning
Civale J,  Rivens I,  ter Haar G,  Morris H,  Coussios C,  Friend P,  Bamber J,  et al. (2013)
Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion with human blood
Waldman JP,  Vogel T,  Burlak C,  Coussios C,  Dominguez J,  Friend P,  Rees MA,  et al. (2013)
Mechanical approaches to oncological drug delivery.
Carlisle R,  Coussios C-C,  et al. (2013)
Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound.
Carlisle R,  Choi J,  Bazan-Peregrino M,  Laga R,  Subr V,  Kostka L,  Ulbrich K,  Coussios C,  Seymour LW,  et al. (2013)
Use of micro- and nano-sized inertial cavitation nuclei to trigger and map drug release from cavitation-sensitive liposomes.
Graham SM,  Myers RS,  Choi J,  Bazan-Peregrino M,  Seymour L,  Carlisle R,  Coussios CC,  et al. (2013)
Goldnanoparticles for the enhancement ofadenovirus stealthing
Mo S,  Myers R,  Carlisle R,  Coussios C,  Seymour L,  et al. (2013)
Increased Adenovirus density for increased ultrasound-mediated delivery to tumors
Carlisle RC,  Mo S,  Myers R,  Graham S,  Mylonopoulou E,  Cawood R,  Seymour LW,  Coussios CC,  et al. (2013)
NORMOTHERMIC PERFUSION OF DISCARDED HUMAN PANCREASES
Friend PJ,  Coussios C,  Ravikumar R,  et al. (2013)
Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model.
Bazan-Peregrino M,  Arvanitis CD,  Rifai B,  Seymour LW,  Coussios C-C,  et al. (2012)
Spatiotemporal monitoring of high-intensity focused ultrasound therapy with passive acoustic mapping.
Jensen CR,  Ritchie RW,  Gyöngy M,  Collin JRT,  Leslie T,  Coussios C-C,  et al. (2012)
Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model
Bazan-Peregrino M,  Arvanitis CD,  Rifai B,  Seymour LW,  Coussios CC,  et al. (2012)
The role of normothermic extracorporeal perfusion in minimizing ischemia reperfusion injury.
Vogel T,  Brockmann JG,  Coussios C,  Friend PJ,  et al. (2012)
Spatiotemporal quantification of therapeutically relevant cavitation for ablation and drug delivery by ultrasound.
Coussios CC,  Jensen C,  Ritchie R,  Gyongy M,  Hockham N,  Rifai B,  Mylonopoulou E,  Choi J,  Collin JR,  et al. (2012)
Acoustic particle manipulation in a 40 kHz quarter-wavelength standing wave with an air boundary.
Trippa G,  Trine S,  Ventikos Y,  Coussios C-C,  et al. (2012)
Ultrasound-enhanced drug delivery for cancer.
Mo S,  Coussios C-C,  Seymour L,  Carlisle R,  et al. (2012)
Thin-film sparse boundary array design for passive acoustic mapping during ultrasound therapy.
Coviello CM,  Kozick RJ,  Hurrell A,  Smith PP,  Coussios C-C,  et al. (2012)
Targeting of liposomes via PSGL1 for enhanced tumor accumulation
Carlisle R,  Seymour LW,  Coussios CC,  et al. (2012)
Determination of Cytotoxic Thermal Dose During HIFU Ablation
Nandlall SD,  Bazan-Peregrino M,  Mo S,  Coussios C-C,  et al. (2012)
Sonosensitive Nanoparticles for Controlled Instigation of Cavitation and Drug Delivery by Ultrasound
Wagstaffe SJ,  Schiffter HA,  Arora M,  Coussios C-C,  et al. (2012)
Significant Skin Burns May Occur With The Use Of A Water Balloon In HIFU Treatment
Ritchie R,  Collin J,  Wu F,  Coussios C,  Leslie T,  Cranston D,  et al. (2012)
CFD modeling of an ultrasonic separator for the removal of lipid particles from pericardial suction blood.
Trippa G,  Ventikos Y,  Taggart DP,  Coussios C-C,  et al. (2011)
HIFU-induced cavitation and heating in ex vivo porcine subcutaneous fat.
Kyriakou Z,  Corral-Baques MI,  Amat A,  Coussios C-C,  et al. (2011)
Real-time passive acoustic monitoring of HIFU-induced tissue damage.
Nandlall SD,  Jackson E,  Coussios C-C,  et al. (2011)
Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion with human blood.
Waldman JP,  Vogel T,  Burlak C,  Coussios C,  Dominguez J,  Friend P,  Rees MA,  et al. (2011)
Hepatic steatosis and normothermic perfusion-preliminary experiments in a porcine model.
Jamieson RW,  Zilvetti M,  Roy D,  Hughes D,  Morovat A,  Coussios CC,  Friend PJ,  et al. (2011)
Hepatic steatosis and normothermic perfusion-preliminary experiments in a porcine model
Jamieson RW,  Zilvetti M,  Roy D,  Hughes D,  Morovat A,  Coussios CC,  Friend PJ,  et al. (2011)
Cavitation-Enhanced Extravasation for Drug Delivery
Arvanitis CD,  Bazan-Peregrino M,  Rifai B,  Seymour LW,  Coussios CC,  et al. (2011)
Cavitation-enhanced extravasation for drug delivery.
Arvanitis CD,  Bazan-Peregrino M,  Rifai B,  Seymour LW,  Coussios CC,  et al. (2011)
Effect of temperature on rectified diffusion during ultrasound-induced heating.
Webb IR,  Payne SJ,  Coussios C-C,  et al. (2011)
Ultrasound-enhanced delivery of polymer-coated oncolytic adenovirus for tumour growth inhibition
Carlisle R,  Choi J,  Kostka L,  Bazan-Peregrino M,  Ulbrich K,  Coussios C,  Seymour L,  et al. (2011)
Sonosensitive nanoparticle formulations for cavitation-mediated ultrasonic enhancement of local drug delivery
Wagstaffe SJ,  Arora M,  Coussios CC,  Schiffter HA,  et al. (2011)
Normothermic Machine Perfusion of the Liver
Vogel T,  Brockmann JG,  Coussios CC,  Friend PJ,  et al. (2011)
An acoustic microscopy technique to assess particle size and distribution following needle-free injection.
Condliffe J,  Schiffter HA,  Cleveland RO,  Coussios C-C,  et al. (2010)
Real-time optical measurement of biologically relevant thermal damage in tissue-mimicking hydrogels containing bovine serum albumin.
Nandlall SD,  Schiffter HA,  Vonhoff S,  Bazán-Peregrino M,  Arora M,  Coussios C-C,  et al. (2010)
Ultrasonic Activation of Thermally Sensitive Liposomes
Mylonopoulou E,  Arvanitis CD,  Bazan-Peregrino M,  Arora M,  Coussios CC,  et al. (2010)
Passive mapping for real-time monitoring of ultrasound therapy.
Coussios CC,  Gyongy M,  Ritchie R,  Webb I,  Nandlall S,  Jackson E,  Arvanitis C,  Bazan-Peregrino M,  Arora M,  et al. (2010)
Exploitation of cavitation-enhanced heating for release of doxorubicin from thermosensitve liposomes by therapeutic ultrasound.
Mylonopoulou E,  Bazan-Peregrino M,  Arvanitis CD,  Coussios CC,  et al. (2010)
Biocompatible solid particles for controlled instigation of cavitation during therapeutic ultrasound.
Arora M,  Schiffter H,  Manhas V,  Wagstaffe S,  Coussios C,  et al. (2010)
Cavitation-enhanced delivery of macromolecules into an obstructed vessel.
Rifai B,  Arvanitis CD,  Bazan-Peregrino M,  Coussios C-C,  et al. (2010)
Dynamics of gas bubbles in time-variant temperature fields
Webb IR,  Arora M,  Roy R,  Payne S,  Coussios C,  et al. (2010)
Robust Capon Beamforming for Passive Cavitation Mapping during HIFU Therapy
Coviello CM,  Faragher S,  Coussios CC,  et al. (2010)
Localization and Interpretation of Bubble Activity during HIFU Exposure
Kennedy P,  Arora M,  Coussios C-C,  et al. (2009)
Normothermic perfusion: a new paradigm for organ preservation.
Brockmann J,  Reddy S,  Coussios C,  Pigott D,  Guirriero D,  Hughes D,  Morovat A,  Roy D,  Winter L,  Friend PJ,  et al. (2009)
Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model.
Holland CK,  Vaidya SS,  Datta S,  Coussios C-C,  Shaw GJ,  et al. (2008)
Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent.
Datta S,  Coussios C-C,  Ammi AY,  Mast TD,  de Courten-Myers GM,  Holland CK,  et al. (2008)
Characterization of ultrasound propagation through ex-vivo human temporal bone.
Ammi AY,  Mast TD,  Huang I-H,  Abruzzo TA,  Coussios C-C,  Shaw GJ,  Holland CK,  et al. (2008)
Use of Passive Arrays for Characterization and Mapping of Cavitation Activity during HIFU Exposure
Gyoengy M,  Arora M,  Noble JA,  Coussios CC,  et al. (2008)
High intensity focused ultrasound: past, present and future.
Haar GT,  Coussios C,  et al. (2007)
The effect of HIFU-relevant rates of heating on the growth and dissolution of nuclei available for inertial cavitation
Webb I,  Arora M,  Collin J,  Payne S,  Roy R,  Coussios C-C,  et al. (2007)
Correlation of cavitation with ultrasound enhancement of thrombolysis.
Datta S,  Coussios C-C,  McAdory LE,  Tan J,  Porter T,  De Courten-Myers G,  Holland CK,  et al. (2006)
Use of controlled acoustic cavitation to enhance and monitor cancer treatment by highintensity focussed ultrasound (HIFU)
Coussios C,  Collin J,  Smith M,  et al. (2006)
Development of an acoustic microscopy technique to assess particle distribution following needle-free injection
Condliffe J,  Collin J,  Carter F,  Costigan G,  Coussios CC,  et al. (2006)
Dynamics and control of cavitation during high-intensity focused ultrasound application
Thomas CR,  Farny CH,  Coussios C,  Roy R,  Holt RG,  et al. (2005)
In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz.
Coussios C-C,  Holland CK,  Jakubowska L,  Huang S-L,  MacDonald RC,  Nagaraj A,  McPherson DD,  et al. (2004)
Impaired O2 unloading from stored blood results in diffusion-limited O2 release at tissues: evidence from human kidneys
Dumbill R,  Rabcuka J,  Fallon J,  Knight S,  Hunter J,  Voyce D,  Barrett J,  Ellen M,  Wiessenbacher A,  Kurnawiam T,  Blonski S,  Korczyk P,  Ploeg R,  Coussios C-C,  Friend P,  Swietach P,  et al. ()