Professor
Robin Cleveland
PhD
Director of Institute of Biomedical Engineering
Professor of Engineering Science
Fellow of Magdalen College
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Tel: 01865 617737
College: Magdalen College
Location: Institute of Biomedical Engineering, Nuffield Orthopaedic Centre, Marcela Botnar Wing, Oxford OX3 7LD
Site: Nuffield Orthopaedic Centre
Research Building: Botnar Research Centre

Robin Cleveland is Professor of Engineering Science and Tutorial Fellow at Magdalen College, Oxford. He received his PhD in Mechanical Engineering from the University of Texas at Austin where his doctoral research was on sonic boom propagation in the atmosphere. Upon completion of his PhD he was award the F.V. Hunt Fellowship of the Acoustical Society of America which he carried out at the University of Washington in Seattle studying shock wave lithotripsy – breaking of kidney stones by shock waves. After two years in Seattle, Robin joined the faculty at Boston University where he remained for fourteen years rising to the rank of Professor of Mechanical Engineering. In 2011 he joined the University of Oxford, working in the BUBBL research group.

Robin carries out research in nonlinear acoustics with particular application to therapeutic uses of biomedical ultrasound.  Recent research areas include: low-intensity ultrasound for transcranial ultrasound neuro-stimulation (TUS), disrupting bacterial biofilms with shock waves, high-intensity ultrasound for thermal ablation, ultrasonic drug-delivery include delivery vehicles, and laser and shock wave lithotripsy for fragmenting kidney stones.

BUBBL: Non-Invasive Therapy & Drug Delivery

Full list on Google scholar

  1. L. E. Goldstein, A. M. Fisher, C. A. Tagge, …, R. O. Cleveland, R. E. Tanzi, P. K. Stanton, A, C. McKee “Chronic Traumatic Encephalopathy in Blast-Exposed Military Veterans and a Blast Neurotrauma Mouse Model,” Science Translational Medicine 4(134):1—16 (2012). doi: 10.1126/scitranslmed.3003716
  2. E. J. Jackson, C.-C. Coussios, R. O. Cleveland, Nonlinear Acoustic Properties of ex vivo Bovine Liver and the Effects of Temperature and Denaturation, Phys. Med. Biol. 59: 3223-3238. (2014). doi: 10.1088/0031-9155/59/12/3223
  3. S. R. Harrogate, L.M.S. Yick, J.C. Williams Jr., R.O. Cleveland, B.W. Turney, Quantification of the range of motion of kidney and ureteric stones during shockwave lithotripsy in conscious patients. J. Endourology 30(4): 406-410 (2016). doi: 10.1089/end.2015.0388
  4. C. A. Tagge, A. M. Fisher, O. V. Minaeva, …, R. O. Cleveland, …., P. K. Stanton, A. C. McKee, L. E. Goldstein Concussion, Microvascular Injury, and Phosphorylated Tauopathy in Young Athletes after Impact Head Injury and an Impact Concussion Mouse Model, Brain 141:422-458 (2018). doi: 10.1093/brain/awx350
  5. Zhang, J., Shrivastava, S., Cleveland, R. O., & Rabbitts, T. H, Lipid-mRNA nanoparticle designed to enhance intracellular delivery mediated by shock waves. ACS applied materials & interfaces, 11: 10481-10491 (2019). doi: 10.1021/acsami.8b21398
  6. S. Qiao, D. Elbes, O. Boubriak, J.P.G Urban, C-C. Coussios, R.O. Cleveland, “Delivering focused ultrasound to intervertebral discs using time-reversal,” Ultrasound in Medicine and Biology 45:2405-2416 (2019). doi: 10.1016/j.ultrasmedbio.2019.04.023
  7. V. Braun, J. Blackmore, R. O. Cleveland, C. R Butler, “Transcranial ultrasound stimulation in humans is associated with an auditory confound that can be effectively masked,” Brain Stimulation 13:1527-1534 (2020). doi: 10.1016/j.brs.2020.08.014
  8. J. Ward, X. Cheng, Y. Xiao, A. Chandrashekar, Oxford Abdominal Aortic Aneurysm (OxAAA) Study, A. Handa, R. O. Cleveland, R. Lee, “Brachial Artery Relaxation Index (BARI): a New Index for Improving the Prediction of Growth of Abdominal Aortic Aneurysm in Humans Using Ultrasound Imaging” PloS one 16:e024803 (2021). doi: 10.1371/journal.pone.0248043
  9. C. R. Butler, E. Rhodes, J. Blackmore, X. Cheng, R. L. Peach, M. Veldsman, F. Sheerin, R. O. Cleveland “Transcranial ultrasound stimulation to human middle temporal complex improves visual motion detection and modulates electrophysiological responses” Brain Stimulation 22:1236-1245 (2022). doi: 10.1016/j.brs.2022.08.022
  10. L. A. Richards, E. Stride, R. O. Cleveland “Foam gratings as an alternative to customised lenses” J. Acoust Soc Am. 153.1:17-25 (2023). doi: 10.1121/10.0016755
  11. JL Rintoul, E. Neufeld, C. Butler, R. O. Cleveland, Nir Grossman, ” Remote focused encoding and decoding of electric fields through acoustoelectric heterodyning.” Communications Physics1: 79 (2023). doi: 10.1038/s42005-023-01198-w
  12. Sara B. Keller, Gareth LuTheryn, Michael D. Gray, Brian Lyons, Robin O. Cleveland, Eleanor Stride, Constantin C. Coussios, Quantitative evaluation of anti-biofilm cavitation activity seeded from microbubbles or protein cavitation nuclei by passive acoustic mapping” Med. Biol.69 215008. doi: 10.1088/1361-6560/ad7f1a
  13. Qiang Wu, Michael Gray, Cameron A. B. Smith, Luca Bau, Robin O. Cleveland, Constantin Coussios, Eleanor Stride,Challenges in classifying cavitation: Correlating high-speed optical imaging and passive acoustic mapping of cavitation dynamics, Acoust. Soc. Am. 156:3608–3620 (2024) https://doi.org/10.1121/10.0034426

  • Chair, 22nd International Symposium of Nonlinear Acoustics, Oxford, 2022.
  • International Scientific chair, 20th Symposium of the International Society of Therapeutic Ultrasound, Gyeongju, Korea 2021.
  • Invited Speaker, British Association of Urological Surgeons Virtual Annual Meeting (2020).
  • Invited Speaker, Frontier Acoustics Symposium, Shenhzen, China (2017)
  • Plenary Speaker, International Symposium on Nonlinear Acoustics, Lyon, France (2015)
  • ASA Bruce Lindsey Award (2000)
  • ASA Hunt Post-Doctoral Fellowship in Acoustics (1995-6)
Featured Publications by Professor Cleveland
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