Transcranial Ultrasound Stimulation (TUS) is emerging as an exciting new tool for non-invasive neuromodulation due to its high spatial resolution (~5mm diameter focus), and the potential to target deep brain structures. TUS employs low energy ultrasound (similar to what is used in diagnostic ultrasound imaging) and has been demonstrated to have modulate brain function in a range of animal models and in number of studies in humans.
Although the mechanisms by which TUS may produce neuromodulation have been identified, further multidisciplinary research is required for the full potential of TUS for treatment of neurological diseases to be achieved. We carry out research running from computational models to human trials in order to advance the understanding of the mechanisms behind TUS and how current and novel protocols can be optimised in the treatment of neurological diseases.