Dr
Joram J. van Rheede
DPhil
EPSRC Open Fellow
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College: Christ Church
Location: IBME
Site: Old Road Campus
Research Building: Old Road Campus Research Building

Dr. Joram J. van Rheede is an EPSRC Open fellow at the Institute of Biomedical Engineering (Department of Engineering Science) and an associate group leader at the Brain Network Dynamics Unit (Nuffield Department of Clinical Neurosciences) at the University of Oxford.

After obtaining a BA in cognitive sciences from Utrecht University in 2007, Joram joined the University of Oxford in 2008 for an MSc + DPhil programme in Neuroscience, defending his doctoral thesis on the role of sensory experience in visual system development in 2013. Following postdoctoral projects on sensory prosthetic technology and neural sensory processing, Joram joined the MRC Brain Network Dynamics Unit to work with Prof. Andrew Sharott in 2020 and joined the Brain Engineering lab to work with Prof. Tim Denison in 2023.

Since 2026 he is an EPRSC Open fellow, with a research programme focusing on the interaction of deep brain stimulation therapy and sleep, and the long-term operation of closed-loop deep brain stimulation algorithms. This includes clinical studies with deep brain stimulation patients as well as preclinical studies in disease models.

Alongside his research appointments, Joram is a Lecturer in Psychology at Christ Church, providing tutorials to undergraduate students of Experimental Psychology, Psychology Philosophy and Linguistics, and Medicine.

  • Understanding the interaction between therapeutic neuromodulation and brain state on clinically relevant time scales
  • Estimation of physiological / pathological state from neural and multi-modal recordings
  • Characterising and improving signal quality in multi-day neural recordings in patients (out of the clinic/lab)
  • Long-term (24/7) operation of closed-loop algorithms for neuromodulation
  • Neurotechnology for long-term closed loop and sleep-aware therapy research

Brain Engineering Lab (IBME; Prof. Timothy Denison)

Sharott Lab (BNDU; Prof. Andrew Sharott)

 

Kirby, M. M., Rheede, J. J. van, Marks, V. S., Dijk, D.-J., Denison, T. J., & Constandinou, T. G. (2026). Review: Circadian Dysfunction, Chronotherapy, and Deep Brain Stimulation (DBS) in Parkinson’s Disease (PD). Preprints, 202605.0290.v1. https://doi.org/10.20944/preprints202605.0290.v1

Piper, R. J., Fleming, J. E., Rheede, J. J. van, Marks, V. S., Landin, K., Costache, D., Hasegawa, H., Selway, R., Richardson, H., Seunarine, K. K., D’Arco, F., Carter, S., Arcaro, C., Moeller, F., Dehbi, H.-M., Valentin, A., Kaliakatsos, M., Denison, T., & Tisdall, M. M. (2026). Feasibility and optimization of a novel, cranially-mounted deep brain stimulation device for children with epilepsy – the CADET Pilot study. Brain Stimulation, 19(4), 103149. https://doi.org/10.1016/j.brs.2026.103149

Tourigny, K., Piper, R. J., Tisdall, M., Neumann, W.-J., Green, A. L., Denison, T., & Rheede, J. van. (2026). A cardiac pulse signal affects local field potentials recorded from deep brain stimulation electrodes across clinical targets. bioRxiv, 2026.02.10.704848. https://doi.org/10.64898/2026.02.10.704848

Marks, V. S., Rheede, J. J. van, Karantonis, D. M., Esteller, R., Dinsmoor, D., Fleming, J. E., Larson, B., Desborough, L., Single, P., Raike, R. S., D’Haese, P.-F., Englot, D. J., Lempka, S. F., North, R., Poree, L., Bikson, M., & Denison, T. J. (2026). Principles of Physiologic Closed-Loop Controllers in Neuromodulation. Neuromodulation: Technology at the Neural Interface. https://doi.org/10.1016/j.neurom.2026.03.010

Benjaber, M., Zamora, M., Toth, R., Fleming, J. E., Landin, K., Marks, V. S., Crockett, R. A., Ryou, J.-W., Deli, A., Green, A. L., Piper, R. J., Tisdall, M. M., Dijk, D.-J., Schiff, N. D., Sharott, A., Purpura, K. P., Baker, J. L., Rheede, J. J. van, & Denison, T. J. (2025). A clinical grade neurostimulation implant for hierarchical control of physiological activity. BiorXiv https://doi.org/10.1101/2025.10.21.683630

Rheede, J. J. van, Alagapan, S., Denison, T. J., Riva-Posse, P., Rozell, C. J., Mayberg, H. S., Waters, A. C., & Sharott, A. (2024). Cortical signatures of sleep are altered following effective deep brain stimulation for depression. Translational Psychiatry, 14(1), 103. https://doi.org/10.1038/s41398-024-02816-z

Wendt, K., Sorkhabi, M. M., O’Shea, J., Denison, T., & Rheede, J. van. (2023). Influence of time of day on resting motor threshold in clinical TMS practice. Clinical Neurophysiology. https://doi.org/10.1016/j.clinph.2023.08.017

Rheede, J. J. van, Feldmann, L. K., Busch, J. L., Fleming, J. E., Mathiopoulou, V., Denison, T., Sharott, A., & Kühn, A. A. (2022). Diurnal modulation of subthalamic beta oscillatory power in Parkinson’s disease patients during deep brain stimulation. Npj Parkinson’s Disease, 8(1), 88. https://doi.org/10.1038/s41531-022-00350-7